CONFERENCE OVERVIEW

“With technological developments advancing at a seemly ever increasing pace, methods of monitoring biological activity  that a decade ago wouldn’t look out of place on Star Trek are beginning to filter into the lab.

How are these being used, what can they tell us and what are the limitations?

 At this conference we will hear talks on the latest cutting edge detection technologies and biological techniques transitioning into screening labs. How are they faring and what might we be using in 10 years time?”

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Click here for delegate registration (places are still available, book now!)

In just over a decade we have moved from ‘simple’ radioactive filter binding assays, through to absorbance cell based assays, fluorescence (in all it flavours), reporter gene assays, second messenger assays, to HCS and now label free detection of cell assays.

These developments have been driven in part, by the emerging understanding of the complexities of sub cellular signalling events and their activation or suppression.

Different formats, even in the same cell line can give widely different values for compound activity, all valid, depending on your frame of reference. To add this, we rarely use native cell types for primary screening, opting through necessity to use highly engineered immortalised cell lines. This can make it difficult to determine what the ‘correct’ assay format for a given target is.

In recent years this has lead to an increasing effort in replicating as closely as possible the cellular processes involved in a disease state under investigation, while maintaining a level or screening “do-ability”. The efficient culture and use of primary cells, differentiated stem cells and 3D culture techniques are all active hot topics of research to address this.

On the instrumentation side we see formats that promise to monitor several pathways simultaneously and deliver knowledge in addition to a simple activation or inhibition events. Add to the mix ever increasing sensitivity, simplification of use, higher throughputs, lower costs or the elimination of need the need to external labels.

At Advances in Cell Based Screening Technologies you will hear about how these advances are being applied to screening and what new technologies we may see emerge and transition to labs over the next few years.

REGISTRATION

Registration is FREE

Spread the word, make sure everyone knows about this meeting, it is the first ELRIG meeting of 2011, don't miss it.  Come along and hear the Leaders of the Industry speaking about the Technological Developments in Cell Based Screening.

SPEAKERS

We now have a full programme of Speakers:-

Yen Choo, Plasticell

Gareth Wayne, GSK

Leo Price, Leiden University

Gary Clark, BioFocus

Henry Danahay, Novartis

Kishan Dholakia, St Andrews University

Fatima Labeed, Surrey University

Frank Craig, Sphere Fluidics

SPEAKER PROGRAMME

8.15  - 9.15	Registration
9.20 –  9.25 9.25 – 9.30	Session Chairs	Conference Director, Opening Remarks Introductions & Welcome  -  Peter Simpson and Del Trezise
9.30 – 10.00	Kishan Dholakia, St Andrews University	A new light on cell screening: emergent Photonics technologies for the 21st century.
10.00 – 10.30	Yen Choo, Plasticell	Stem Cell differentiation using Small Molecules
10.30 – 11.00	COFFEE BREAK – EXHIBITION
11.00 – 11.30	Frank Craig, Sphere Fluidics	A Miniaturised Discovery System Based on Picodroplets
11.30 – 12.00	Gareth Wayne, GSK	Taqman-Based Enhanced Sensitivity Immunoassays for Drug Discovery
12.00 – 12.30	Snapshots	TAP, Essen BioScience, Solentim, GE
12.30– 2.30	LUNCH  + EXHIBITION & POSTER VIEWING
2.30 – 3.00	Leo Price, Leiden Drug Research Centre	Functional genomics and compound screening in organotypic 3D cell cultures
3.00 – 3.30	Gary Clark, BioFocus	Using microfluidics for the next generation of automated ion channel screening platforms
3.30 – 4.00	COFFEE BREAK – EXHIBITION
4.00 – 4.30	Fatima Labeed, Surrey University	Di-electrophoresis (DEP) for Ion Channel, toxicology and Stem Cell Differentation
4.30 – 5.00	Henry Danahay, Novartis	High Throughput Screening of Organotypic Lung Cultures
5.00 – 5.15	CLOSE -  PRIZE DRAW

CAREERS ZONE

In view of the recent site closures announced in our Industry, we recognise that more and more people may be looking to ELRIG as a way of networking and seeking job opportunities, especially as our events are completely FREE.

If you are a potential cnadidate, we will have a skills posting area, jobs vacant boad, representatives from several different scientific recruitment agencies and people on hand of offer 1-to-1 advice (in private if you prefer).

We usually run the Careers Zone at our larger shows, offering career and job advice to the Scientific community. 

POSTERS

Poster Boards are 2m High and 1m Wide

We have received 12 Academic Posters - a record for a one day show.

EXHIBITORS

SOLD OUT:

4titude Ltd

Beckman Coulter UK Ltd

Bellbrook Labs

Berthold Detection Systems GmbH

Bigneat Ltd

Biostatus

BMG Labtech Ltd

Caltag Medsystems Ltd

Cambridge Bioscience

CCS Cell Culture Service

Cellaura Technologies

Cisbio Bioassays

Corning Life Sciences Europe

Cyntellect

Essen BioScience Ltd

Fluidx

GE Healthcare

Gilson Scientific Ltd

Greiner Bio-One

HighRes Biosolutions Ltd

HPA Culture Collections

InSphero AG

Labcyte

Labtech International

Lonza Cologne GmbH

Molecular Devices (UK) Ltd

Perkin Elmer LAS (UK) Ltd

Porvair Sciences Ltd

Process Analysis and Automation

Roche Diagnostics Limited

The Automation Partnership  

Thermo Scientific                                                                                                                                                                        

Wildcat Laboratory Solutions / Kbiosystems

Solentim                    Synthelis

HOTEL LIST

CrownePlaza, Downing Street, Cambridge CB2 3DT Tel:     01223 464466 Fax:     01223 464440	CambridgeshireGarden MoatHouseHotel GrantaPark Mill Lane Cambridge CB2 1RT Tel:   01223 259988 Fax: 01223 316605
DeVereUniversityArms Regent Street Cambridge CB2 1AD Tel:   01223 351241 Fax:   01223 315256	Royal Cambridge Hotel Trumpington Street Cambridge CB2 1PY Tel:   01223 351631 Fax: 01223 352972
Gonville Hotel Gonville Place Cambridge CB1 1LY Tel:   01223 366611 Fax: 01223 315 470	Arundel House Hotel Chesterton Road Cambridge CB4 3AN Tel: 01223 367701 Fax: 01223 367721
The Saffron Hotel 8-12 High Street Saffron Walden Tel: 01799 522676 Fax: 01799 513979	The Crown House Hotel Great Chesterford Saffron Walden Tel: 01799 530515 Fax: 01799 530683
Duxford Lodge Hotel Ickleton Road Cambridge Tel: 01223 836444 Fax: 01223   832271	Red Lion Hotel Station Road Whittlesford Cambridge Tel:   01223 832115
Travel Lodge Fourwentways A11, 6mSouth CambridgeTel: 08700 850950	Holiday Inn Express Cambridge-Duxford 42 Station Road  Whittlesford Cambridge CB22 4NL Tel:  01223 497070 email:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Hinxton Hall: Reservations:   call 01223 495003

How to Get There: :

By car from the South: Leave the M11 at junction 9 and take the A1301 towards Cambridge. From the Stumps Cross roundabout system take the first left (about 800m). At the next small roundabout follow the signpost for 'Genome Campus'

By car from the North: Leave the M11 at junction 10 (note that M11 junction 9 is restricted and accessible from the South only). Travel a mile or so on the A505 in the direction of Saffron Walden to a roundabout and take the third exit (A1301 towards Saffron Waldron). Pass two turnings to Hinxton, and take the next right, a small roundabout, signposted to Genome Campus.

By Train: Cambridge is on the main line from London Kings Cross. Whittlesford, Great Chesterford and Audley End stations are on the line from London Liverpool Street to Cambridge. Journey time from London is under an hour.

Please note that Whittlesford and Great Chesterford stations do not have a taxi rank or telephone. Please use either Cambridgeor Audley End stations if a taxi has not been pre-booked.

Timetables available from Railtrack

By air:
London Stansted is about a 30 minute drive to Hinxton.
London City and London Luton are approximately 1 hours drive.
London Heathrow and London Gatwick are about two hours drive.

Low cost airline "Go", Ryanair, KLMuk, Virgin Express, KLM's Buzz, and SAS all land in Stansted and fly from most of the larger European cities.

Web sites for no-frills airlines landing in Stansted:
http://www.ryanair.com
http://www.buzzaway.com
http://www.go-fly.com

For more travel information to and from the airports try gobycoach.com or railtrack.co.uk

Local Taxi Companies:
Phil's Taxi Services	Telephone: 01223 521918
Academy	Telephone: 08000 191022
Panther Taxis	Telephone: 01223 715715
Diamond Taxis	Telephone: 01223 523523
A1 Taxis	Telephone: 01223 525555
A&M Carriages (Airport Specialist)	Telephone: 01223 513703
MasterCab (Airport Specialist)	Telephone: 01223 566654

Approximate Taxi Prices:
Cambridge - Hinxton £15.00
Audley End - Hinxton £12.00
Stansted - Hinxton £22.00
Luton - Hinxton £45.00
London City - Hinxton £50.00
Heathrow - Hinxton £80.00
Gatwick - Hinxton £90.00

(Prices are based on the local companies listed above)

Hinxton Hall:

Conference Centre Postal Address:

Hinxton Hall Conference Centre

Wellcome Trust Genome Campus

Hinxton

Cambridge

CB10 1RQ

Conference Reception Desk: Tel: +44 (0)1223 495000

Email:  This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Website: http://www.hinxton.wellcome.ac.uk

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