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Chun-wa Chung, GSK
Written by Jackie Howard Tuesday, 08 May 2012 10:59
Pick and mix : optimizing the choice of biophysical and biochemical for fragment screening
An ever growing array of biophysical and biochemical methods have been proposed for fragment lead identification. Reviewing in house and literature comparative studies this talk outlines the pros and cons of various biophysical and biochemical screening approaches. Examples of how these considerations can be used to design an effective assay cascade and results are given. Finally opportunities for technology improvement are highlighted.