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DRUG DISCOVERY - 2008

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Bournemouth International Centre  (BIC)

23rd - 24th September 2008

Conference Overview 

Following our highly successful meeting in 2007, the European Laboratory Robotics Interest Group (ELRIG) and the Society of Biomolecular Sciences (SBS), are pleased to announce that their Drug Discovery: 2008  Meeting will be held at the Bournemouth International Centre,  (BIC), UK, on 23rd-24th September 2008.  

This conference will encompass six sessions in two days. Each will focus on a different area of Drug Discovery from selecting compounds for the corporate collection, liquid handling and detection technologies, plus advances in assay development and screening. Two sessions will address the biochemistry of two important different target classes: Enzymes and G-protein coupled receptors. Biopharmaceuticals will form the sixth session. As with our highly successful meeting in 2007, attendees will hear world class speakers discussing the challenges facing the drug discovery scientist.  The scientific sessions will be complemented by plenary keynote presentations from two of the field's foremost researchers, a poster session and a vendor exhibition with over 80 exhibitors.

Bournemouth has always enjoyed the highest reputation as a premier conference and entertainment destination, and has now developed into a thriving cosmopolitan resort, attracting many £millions of investment into the town's Business Tourism and Leisure facilities, with new hotels, restaurants, bars, clubs and attractions opening on a regular basis to serve both local residents and the growing number of visitors every year. 

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Program Chairs

Adrian Kinkaid - Lectus Therapeutics

Steve Rees - GlaxoSmithKline

 

Keynote Speakers

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   Anton Simeonov, NIH

 

 

Sessions: 

      Pre-event - Monday 22nd September

      Day 1 - Tuesday 23rd September

  • Drug Discovery for Enzyme Targets
  • Compound Management Diversifying the Corporate Collection
  • The Hard Cell: Current issues in Drug Discovery and Screening

      Day 2 - Wednesday 24th September

  • Liquid Handling and Detection Technologies
  • Biopharmaceutical Drug Discovery
  • Drug Discovery for GPCR Targets

 

CONFERENCE PROGRAMME – TALK TITLES

 

Day 1

 

 

SESSION 1

Drug Discovery for Enzyme Targets

SESSION 2

Compound Management Diversifying the Corporate Collection

SESSION 3

The Hard Cell:  Current issues in Drug Discovery and Screening

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Introduction & Welcome

9.15 – 9.30

 

Adrian Kinkaid, Lectus Therapeutics & Steve Rees, GlaxoSmithKline

9.30 - 10.15

Keynote Presentation

Dan Bajonic, Novartis

10.15 - 10.45

COFFEE BREAK

Session Chairs Introduction

10.50 - 11.00

Andreas Sewing

and Niall Martin

Stephen Garland

and Jeff Paslay

Richard Eglen

and Martin Coldwell

 

11.00 - 11.30

Spencer Campbell, Arrow Therapeutics

‘The challenges of viral enzymes as drug discovery targets'

Paul Leeson, AstraZeneca

'Physiochemical Properties and Library Design'

Mark Thiede, Pfizer

'Stem cell applications and opportunities in drug discovery'

11.30 - 12.00

Namir Hassan, GSK

'Adapting the baculovirus expression system to a novel cellular kinase assay format'

Nunzio Sciammetta, Pfizer


‘An Integrated Approach to Drug Discovery in the 21st Century; Working beyond our walls'

 

Kathy Dodgson, AstraZeneca

'Experiences of the Application of Label-Free Technologies for compound profiling in cell- base assays'

12.00 - 12.30

Stephan Heyse, Genedata

 

Zoe Blaxill, GSK


‘Maintaining a High Quality Compound Collection: The GSK Experience'

 

Steve Rees, GSK

‘Cell Based Screening for GPCR Ligands; Strategies, Successes and Future Challenges'

Snapshots

12.30 - 13.00

Caliper Life Sciences

IDBS

Domainex

IOTA Pharma

Beactica

BioFocus

Mettler-Toledo

Molecular Devices

Promega

Millipore

13.00 - 14.30

LUNCH & POSTER EXHIBITION

14.30 - 15.00

 

 

Sir Philip Cohen

The University of Dundee

'Protein Kinases of the innate immune system as drug targets'

 

Ijen Chen, Vernalis

'Libraries for Fragment Screening'

Stefan Prectl, Bayer

'HCA Applications for an effective project support in preclinical drug research'

15.00 - 15.30

Justin Bryans, MRCT

‘Building a high quality screening library from commercial sources'

 

Julie Frearson, Dundee University

"Influencing stem cell behaviour with small molecules: a
functional screening approach"

15.30 - 16.15

COFFEE BREAK

16.15 - 16.45

Ulf Boemer, Bayer

‘Strategies for Kinase inhibitor Discovery'

Jeff Paslay, Wyeth

'To Serve & Protect: Compound Management for Discovery Research'

Magalie Rocheville, GSK

'High precision, efficacy based SAR compound profiling for GPCR targets'

16.45 - 17.15

Nicola Curtin, CRUK

'Inhibition of poly(ADR-ribose) polymerse - a case history'

Steve Garland, GSK

'Application of Chemogenomics to Compound Design'

Dan Leggate, Cellzome

'Development of KinobeadsTM assays for lead optimisation'

17.15 - 19.15

DRINKS RECEPTION, sponsored by SelectScience

   

Day 2

 

 

SESSION 4

Liquid Handling and Detection Technologies

SESSION 5

Biopharmaceutical Drug Discovery

SESSION 6

Drug Discovery for GPCR Targets

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Session Chairs

Introduction

 

8.30 - 8.40

 

Graeme Daniels/Eric Tang/John Comley

 

Sandra Turconi and Richard Pither

 

Stephen Hill and  Fiona Marshall

 

 

8.40 - 9.10

Rochdi Bouhelal, Novartis   

 

FDSS7000, a novel 1536 well multi-readout cellular assay platform for kinetic assays’

Trevor Wattam, GSK

‘Monoclonal Antibody Generation with LIMS and Automation integration’

Annette Gilchrist, Caden Bio

New Tools for Studying GPCR Targets’

9.10 - 9.40

Sabrina Corazza, Axxam    

 

 ‘HTS operations:  How to choose the right components?’

Joost Kolkman, Ablynx    

 

Nanoclone®: A novel high-throughput technology for isolating heavy chain antibody variable domains from single B-cells’

Fiona Marshall, Heptares Therapeutic  

 

 ‘Engineering stabilised GPCRs in agonist and antagonist conformations’

9.40 - 10.10

Kevin Lowitz, Invitrogen

‘Leveraging Hybrid Microplate Detection to Optimize Enabling Assay Technologies for Cell Signaling and Membrane Targets’

Alastair Lawson, UCB  

 

 'Antibodies as Therapeutics and Tools in Drug Discovery'

Stephen Hill, Nottingham University  

 

Pathway specific pharmacology of beta-adrenoceptor ligands  

10.10 - 11.00

COFFEE BREAK

11.00 - 11.30

Eric Tang, AstraZeneca

'Accurate compound dosing in Cell-based assays: Application of acoustic Drop Ejection Technology'

Rosemary Sasse, GSK

 

‘High density screening of domain antibodies’

Gebhard Schertler, Cambridge

‘Structure of the Beta Adrenergic Receptors: Progress in obtaining recombinant G protein Coupled Receptor Structure’

Snapshots
11.30 - 12.00

Matrical, Beckman Coulter, Perkin Elmer, FluidX, Formulatrix, P.R.S.

Paula Harrison, MedImmune 

 

 ‘Screening Biologics in Cell Based Assays’

Evotec, Sibiscreen, DiscoverX, BMG Labtech

12.00 - 1.30

LUNCH & POSTER EXHIBITION

13.30 - 14.00

Daniel Rines, Genomics Institute of the Novartis Research Foundation

'Challenges in Liquid Handling to support routine Miniaturised ultra-High Throughput Screening and Profiling'

Robert Karlsson, GE Healthcare

 

 

'The Application of SPR and Kinetic Screening to Antibody selection' 

Martyn Wood, GSK


‘Label-free technology fulfilling the potential for GPCR drug discovery’

14.00 - 14.30

Florian Hollfelder, Cambs Uni


Integrated Systems for Chemical and Biological Experiments in Microfludic Microdroplets

Matthew Baker, Antitope

'Overcoming Adverse Immunogenicity Against Therapeutic Antibodies'

Carrie Jones, Vanderbilt Uni

‘Development of Allosteric Modulators of GPCSs as a Novel Approach for the Treatment of CNS Disorders’

14.30 - 15.00

COFFEE BREAK

15.00 - 15.45

Keynote Presentation

Anton Simeonov, NIH (NCGC)

15.45 - 16.15

 

Conference Close, Steve Rees (SBS), and Adrian Kinkaid (ELRIG)

Feedback From Prize Draw


  

The Conference Programme timings are  9am - 5pm each day

The Exhibition timings are  8.30 - 7pm on Day 1  and 8.30 - 5pm on Day 2

 

Download an event timetable

 

A timetable of events is now available in PDF format.  Click here to download

 

Registration

 

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Training

If you are interested in running a Training Course at this meeting please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Exhibition

Set Up Time is Monday 22nd September from 8am - 10pm.

This is set to be the largest Drug Discovery show in Europe this year.

The Exhibition is now SOLD OUT. 

 

CURRENT EXHIBITOR LIST 

Anachem Genedata PAA
Astech Projects Genetix Perkin Elmer
Axxam Genevac Porvair
BD Biosciences Gentronix Promega
Beckman Coulter Grace Davison Discovery Qiagen
Bigneat Greiner Bio-one RTS
Biomol International Hamamatsu Redd & Whyte
BIS / Titertek Hamilton Retisoft
BMG Labtech High Res BioSolutions Roylan Developments
Caliper Life Sciences IDBS SelectScience
Cell Culture Services Innovadyne Seltek Consultants
Cell Aura Technologies Invitrogen Sci Med
Cisbio KBioscience Scottish Biomedical
Computype Kbiosystems Sibion
Corning Labcyte SpinX-Technologies
Cybio Lab Services SRU Biosystems
Cyprotex Liconic TAP
Digilab Genomic Solutions Lonza
Tebu-Bio
DiscoverX Matrical EU Tecan
Dotmatics Mettler-Toledo ThermoScientific
ECACC    Molecular Devices -- part of MDS Analytical Technologies Titian Software
Eppendorf   Micronic Tocris Bioscience
Essen Instruments  Millipore TTP Labtech
Fluidx   Nanoscreen Velocity11
ForteBio Inc Nexus Biosystems Zinsser Analytical 
GE Healthcare Northstar Scientific  
 

 

Innovation Zone

The Drug Discovery and Life Sciences sector has been an incubator for technology innovation, start-up businesses and entrepreneurship. In order to provide support in these areas the European LRIG has decided to set up an Innovation Zone within the joint ELRIG/SBS Drug Discovery 2008 Symposia.

 

The Innovation Zone will provide a number of £750.00 2x1m tabletops at the significantly reduced cost of £100.00. These tabletops are on offer to start-up emerging businesses assessed as progressing relevant new technology innovations and entrepreneurship.

Contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

 

CURRENT INNOVATION ZONE

Ash Biotech
Biostatus
DotMatics
Edge Software Consultancy
Progressive Research Systems Ltd
UK Robotics
WildCat
Ziath


Award Committee

 

lightbulbcartoon.jpgAlong with a prize for best poster, ELRIG is proud to be able to begin awarding bursaries for best innovative ideas and new concepts.

Students, academic researchers and industry Scientists/Engineers are all actively encouraged to come forward with proposals which will be reviewed by our award committee and financial help may be awarded.

All you need to do is fill in the application form, giving details on the aim of the project, the plan on how you will acheive your goals, and an idea of cost associated with the project.

The ELRIG award commitee will review the proposal and award some money (up to £2,000) accordingly.

Completed application forms should be e-mailed to This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Sponsorship

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If you are interested in taking Sponsorship at this meeting please contact This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

 

Posters

Click here to submit an abstract.   Abstracts will be reviewed by the Scientific Committee.  Deadline for Poster Abstracts is 31 July 2008.

 

Hotels in Bournemouth

Click below to download an accomodation booking form (pdf format)

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For further information call Jackie Howard on 07879 050 555.



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